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Khabarovsk virus
Khabarovsk virus (KBR) is a novel hantavirus in the Bunyaviridae family isolated from Microtus fortis discovered in far-east Russia. It is an enveloped, negative-sense RNA virus. 〔Hörling J, Chizhikov V, Lundkvist A, Jonsson M, Ivanov L, Dekonenko A, Niklasson B, Dzagurova T, Peters CJ, Tkachenko E, Nichol S.Khabarovsk virus: a phylogenetically and serologically distinct hantavirus isolated from Microtus fortis trapped in far-east Russia. J Gen Virol. 1996 Apr;77 ( Pt 4):687-94.〕
== Virology ==
Two strains of KBR were isolated in Microtus fortis trapped in the Khabarovsk region of far-eastern Russia. The nucleotide sequences revealed that the two isolates were closely related to each other but distinct from all other hantaviruses. Phylogenetic analysis showed that these strains form a separate branch in the Hantavirus tree, positioned between the branches of Prospect Hill and Puumala viruses. Puumala virus was the closest relative, both genetically and serologically. 〔Hörling J, Chizhikov V, Lundkvist A, Jonsson M, Ivanov L, Dekonenko A, Niklasson B, Dzagurova T, Peters CJ, Tkachenko E, Nichol S.Khabarovsk virus: a phylogenetically and serologically distinct hantavirus isolated from Microtus fortis trapped in far-east Russia. J Gen Virol. 1996 Apr;77 ( Pt 4):687-94.〕〔Plyusnin, A., Vapalahti, O., Ufves, K., et al. Sequences of wil Puumala virus genes show a correlation of genetic variation with geographic origin of the strains. Journal of General Virology 75, 405-409. 〕〔Reip, A., Haring, B., Sibold, C., et al. Coding strategy of the M and S genomic segments of a hantavirus representing a new subtype of the Puumala virus serotype. Archives of Virology 140, 2011-2026. 〕
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